Evaluation of the Abbott BinaxNOW rapid antigen 

Analysis of the Abbott BinaxNOW fast antigen check for SARS-CoV-2 an infection in kids: Implications for screening in a faculty setting

Background: Fast antigen assessments maintain a lot promise to be used within the college atmosphere. Nevertheless, the efficiency of those assessments in non-clinical settings and amongst one of many principal goal populations in schools-asymptomatic children-is unclear. To deal with this hole, we examined the optimistic and adverse concordance between the BinaxNOW™ fast SARS-CoV-2 antigen assay and an RT-PCR check amongst kids at a community-based Covid-19 testing web site.

Strategies: We performed fast antigen (BinaxNOW™) and oral fluid RT-PCR (Healing Labs) assessments on kids presenting at a walk-up testing web site in Los Angeles County from November 25, 2020 to December 9, 2020. Constructive concordance was decided because the fraction of RT-PCR optimistic contributors that had been additionally antigen optimistic. Adverse concordance was decided because the fraction of RT-PCR adverse contributors that had been additionally antigen adverse. Multivariate logistic regression fashions had been used to look at the affiliation between optimistic or adverse concordance and participant age, race-ethnicity, intercourse at beginning, signs and Ct values.

Outcomes: 226 kids examined optimistic on RT-PCR; 127 kids or 56.2% (95% CI: 49.5% to 62.8%) of those additionally examined optimistic on the fast antigen check. Constructive concordance was greater amongst symptomatic kids (64.4%; 95% CI: 53.4% to 74.4%) in comparison with asymptomatic kids (51.1%; 95% CI: 42.5% to 59.7%). Constructive concordance was negatively related to Ct values and was 93.8% (95% CI: 69.8% to 99.8%) for kids with Ct values lower than or equal to 25. 548 kids examined adverse on RT-PCR; 539 or 98.4% (95% CI: 96.9% to 99.2%) of those additionally examined adverse on the fast antigen check. Adverse concordance was greater amongst asymptomatic kids.

Conclusions: Fast antigen testing can efficiently determine most COVID infections in kids with viral load ranges more likely to be infectious. Serial fast testing could assist compensate for restricted sensitivity in early an infection

 

Analysis of fast SARS-CoV-2 antigen assessments, AFIAS COVID-19 Ag and ichroma COVID-19 Ag, with serial nasopharyngeal specimens from COVID-19 sufferers

 

We evaluated the diagnostic accuracy of two newly developed, point-of-care, fast antigen assessments (RATs) for detecting SARS-CoV-2, the AFIAS COVID-19 Ag and the ichromaTM COVID-19 Ag, and investigated antigen kinetics. A complete of 200 serially collected nasopharyngeal (NP) specimens from 38 COVID-19 sufferers and 122 specimens from adverse controls had been analyzed. Diagnostic sensitivity and specificity had been assessed compared to molecular check outcomes and subdivided in keeping with focused genes (E, RdRP, and N) and days post-symptom onset (PSO). For the kinetics analysis, cut-off-indices from serial NP specimens had been used in keeping with the variety of days PSO.

Each RATs confirmed sensitivity of 91.3‒100% for specimens with cycle threshold (Ct) < 25. The specificity of AFIAS was 98.7‒98.9% and that of ichromaTM was 100.0%. The kappa values of AFIAS and ichromaTM for the molecular testing of specimens with Ct < 25 (RdRP) had been 0.97 and 1.00, respectively. The sensitivity of AFIAS and ichromaTM for all genes was decrease for specimens collected at 8‒14 PSO than for these collected earlier than 7-days PSO. The kinetics profiles confirmed that antigen ranges progressively decreased from ≤ 7-days PSO to > 22-days PSO. Each RATs confirmed glorious specificity and acceptable sensitivity for NP specimens with greater viral hundreds and for specimens collected inside 7-days PSO. Therefore, they’ve the potential to turn out to be helpful instruments for the early detection of SARS-CoV-2. Nevertheless, due to considerations about false negativity, RATs needs to be used along side molecular assessments.

m-icab
m-icab

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Helicobacter Pylori Antigen

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H. Pylori Rapid Stain (1-Step)

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Dog Toxoplasmosis Antigen Rapid Test Kit

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Dog Toxoplasmosis Antigen Rapid Test Kit

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Canine Parvovirus Antigen Rapid Test Kit

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Description: This kit adopts the sandwich method and the technical principle of colloidal gold immunochromatography to qualitative determine the SARS-CoV-2 antigen. During the test, the sample is dropped into the sample well, and chromatography is performed under the capillary effect. The SARS-CoV-2 antigen in the sample combined with the colloidal goldlabeled SARS-CoV-2 monoclonal antibody I, and then spread to the test area. It is captured by another coated antibody (SARS-CoV-2 monoclonal antibody II), to form a complex and gather in the test area (T line). The quality control area is coated with the goat antimouse antibody, and the colloidal gold-labeled antibody is captured to form a complex and aggregate in the quality control area (C line). If the C line does not show color, it indicates that the result is invalid, and this sample needs to be tested again.

SARS-CoV-2 Antigen Rapid Test Kit

CoV2Ag-25 25T/kit
EUR 42
Description: This product is used for in vitro qualitative detection of SARS-CoV-2 antigen in human oropharyngeal swabs, nasal swabs and nasopharyngeal swabs. It is helpful as an aid in the screening of early mild, asymptomatic, or acute patients for identification of SARS-CoV-2 infection.

SARS-CoV-2 Antigen Rapid Test Kit

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SARS-CoV-2 Antigen Rapid Test Kit

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Adenovirus Antigen and Rotavirus Antigen Rapid Test Kit

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Rapid Response COVID-19 Saliva Rapid Antigen Test

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Description: Rapid Response COVID-19 Saliva Rapid Antigen Test

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Dengue Virus NS1 Antigen Rapid Test Kit

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Dengue Virus NS1 Antigen Rapid Test Kit

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NOVATest Antigen Rapid Test Kit (For Single Use) (NOVA Test)

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Description: COVID-19 Antigen Rapid Test Pen (Saliva)

NOVATest Antigen Rapid Kit (NOVA Test)

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Feline Herpesvirus (FHV) Antigen Rapid Test Kit

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Canine Distemper Virus Antigen Rapid Test Kit

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Canine Distemper Virus Antigen Rapid Test Kit

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Canine Distemper Virus Antigen Rapid Test Kit

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Canine Influenza Virus Antigen Rapid Test Kit

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Canine Influenza Virus Antigen Rapid Test Kit

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Human Candida albicans Antigen Rapid Test Kit

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Human Candida albicans Antigen Rapid Test Kit

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Newcastle Disease Virus Antigen Rapid Test Kit

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Malaria PF and PV Antigen Rapid Test Kit

abx092211-100l 100 µl
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Malaria PF and PV Antigen Rapid Test Kit

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Malaria PF and PV Antigen Rapid Test Kit

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Typhoid Antigen (S. typhi) Rapid Test Kit

abx092222-100l 100 µl
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Typhoid Antigen (S. typhi) Rapid Test Kit

abx092222-1ml 1 ml
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Typhoid Antigen (S. typhi) Rapid Test Kit

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Feline Panleukopenia Virus Antigen Rapid Test Kit

abx092136-100l 100 µl
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Feline Panleukopenia Virus Antigen Rapid Test Kit

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Feline Panleukopenia Virus Antigen Rapid Test Kit

abx092136-200l 200 µl Ask for price

Malaria (Plasmodium Falciparum Antigen) Rapid Test Kit

abx090709-100l 100 µl
EUR 1312.5

Malaria (Plasmodium Falciparum Antigen) Rapid Test Kit

abx090709-1ml 1 ml
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Malaria (Plasmodium Falciparum Antigen) Rapid Test Kit

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Prostate Specific Antigen (PSA) Rapid Test Kit

abx092266-100l 100 µl
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Prostate Specific Antigen (PSA) Rapid Test Kit

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Prostate Specific Antigen (PSA) Rapid Test Kit

abx092266-200l 200 µl
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Classical Swine Fever Virus Antigen Rapid Test Kit

abx092127-100l 100 µl
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Classical Swine Fever Virus Antigen Rapid Test Kit

abx092127-1ml 1 ml Ask for price

Classical Swine Fever Virus Antigen Rapid Test Kit

abx092127-200l 200 µl Ask for price

Accu-Tell COVID-19 IgG/IgM Rapid Test

GEN-B352-20tests 20 tests
EUR 283.2
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus.

Accu-Tell COVID-19 IgG/IgM Rapid Test

GEN-B352-40tests 40 tests
EUR 385.2
Description: A rapid test for detection of antibodies (IgG and IgM) for 2019-nCoV, the novel Coronavirus from the Wuhan strain. The test is easy to perform, takes 10 minutes to provide reliable results and is higly specific to the 2019-nCoV Coronavirus.

SARS-CoV-2 Rapid Antigen Test Nasal

9901-NCOV-03G 25 Tests/Kit
EUR 112.8
Description: The SARS-CoV-2 Rapid Antigen Test is a lateral fl ow rapid chromatographic immunoassay for the qualitative detection of nucleocapsid antigen to SARS-CoV-2 present in human nasal samples. This test is intended for use as an aid in detection of SARS-CoV-2 infection in individuals suspected of COVID-19 with clinical symptoms onset within 5 days. Results are for the identification of SARS-CoV-2 nucleocapsid antigen. Antigen is generally detectable in human nasal swab samples during the acute phase of infection. Positive results indicate the presence of viral antigens, but clinical correlation with patient history and other diagnostic information is necessary to determine infection status. Positive results do not rule out bacterial infection or co- infection with other viruses. The agent detected may not be the definite cause of disease. Negative results should be treated as presumptive, and do not rule out SARS-CoV-2 infection and should not be used as the sole basis for treatment or patient management decisions, including infection control decisions. Negative results should be considered in the context of a patient’s recent exposures, history and the presence of clinical signs and symptoms consistent with COVID-19, and confirmed with a molecular assay, if necessary, for patient management. The SARS-CoV-2 Rapid Antigen Test is intended for use in laboratory or POC settings by healthcare professionals, or self-collection under the supervision of a healthcare worke

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abx092218-100l 100 µl
EUR 775

Respiratory Syncytial Virus (RSV) Antigen Rapid Test Kit

abx092218-1ml 1 ml
EUR 9000

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abx092218-200l 200 µl
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Canine Parvovirus Antigen (CPV Ag) Rapid Test Kit

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EUR 16.1
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abx090713-100l 100 µl
EUR 650

Human Influenza A/B Virus Antigen Rapid Test Kit

abx090713-1ml 1 ml
EUR 10500

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abx090713-200l 200 µl
EUR 2100

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abx092096-20tests 20 tests
EUR 477.6

Canine Coronavirus Antigen (CCV Ag) Rapid Test Kit

HG003 10 Tests/Kit
EUR 16.1
Description: Contents: (1) 10 Tests/Kit   (cassette,disposable dropper,desiccant) (2) 10 Assay buffer tubes (3) 10 Sterile swabs (4) 1 Instruction manual

Feline Herpesvirus Antigen (FHV Ag) Rapid Test Kit

HG005 10 Tests/Kit
EUR 16.1
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HG030 10 Tests/Kit
EUR 21
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Foot and Mouth Disease Virus Antigen Rapid Test Kit

abx092115-100l 100 µl
EUR 487.5

Foot and Mouth Disease Virus Antigen Rapid Test Kit

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Feline Coronavirus Antigen (FCoV Ag) Rapid Test Kit

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EUR 21
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Group A Streptococcus Antigen (GAS) Rapid Test Kit

abx092250-100l 100 µl
EUR 2275

Group A Streptococcus Antigen (GAS) Rapid Test Kit

abx092250-1ml 1 ml
EUR 30000

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abx092250-200l 200 µl
EUR 7800

Human Monkeypox Virus Antigen (MPXV) Rapid Test Kit

abx092162-100l 100 µl
EUR 1000

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abx092162-1ml 1 ml
EUR 12000

Human Monkeypox Virus Antigen (MPXV) Rapid Test Kit

abx092162-200l 200 µl
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abx092174-100l 100 µl
EUR 437.5

Peste des Petits Ruminants Virus Antigen Rapid Test Kit

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Peste des Petits Ruminants Virus Antigen Rapid Test Kit

abx092174-200l 200 µl Ask for price

Porcine Transmissible Gastroenteritis Virus Antigen Rapid Test Kit

abx092131-100l 100 µl
EUR 300

Porcine Transmissible Gastroenteritis Virus Antigen Rapid Test Kit

abx092131-1ml 1 ml Ask for price

Porcine Transmissible Gastroenteritis Virus Antigen Rapid Test Kit

abx092131-200l 200 µl Ask for price

Avian Influenza Virus Antigen Rapid Test Kit (Colloidal gold)

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EUR 518.4

Coronavirus (SARS-Cov-2) Antigen Rapid Test Device (Saliva)

IOV87952 20T/kit
EUR 46.8
Description: Coronavirus (SARS-Cov-2) Antigen Rapid Test Device (Saliva) is an in vitro diagnostic test for the qualitative detection of novel coronavirus antigens in human saliva, using the rapid immunochromatographic method. The identification is based on the monoclonal antibodies specific for the novel coronvirus antigen. It will provide information for clinical doctors to prescribe correct medications.

Fast Antigen Detection Check for Extreme Acute Respiratory Syndrome Coronavirus 2: Tips on how to Use It Correctly?

Circumstances of coronavirus illness 2019 (COVID-19) in Indonesia are nonetheless growing and even greater in the previous few weeks. Contact tracing and surveillance are necessary to find circumstances in the neighborhood, together with asymptomatic people. Analysis of COVID-19 relies upon on the detection of viral RNA, viral antigen, or not directly, viral antibodies. Molecular analysis, utilizing actual time, reverse transcriptase polymerase chain response (RT-PCR), is the widespread customary technique; nonetheless, it’s not broadly out there in Indonesia and requires a excessive customary laboratory.

Fast, point-of-care antibody testing has been broadly used instead; nonetheless, interpretation of the outcomes isn’t easy and now it’s now not utilized by the Indonesian authorities as a screening check for individuals travelling between areas. Thus, the fast antigen detection check (Ag-RDT) is utilized by the Indonesian authorities as a screening check for travellers. Consequently, many individuals purchase the package on-line and carry out self-Ag-RDT at house.

This raises the query of how protected and correct it’s to carry out self-Ag-RDT at house. Earlier than a check is utilized, it’s recommended to analysis its sensitivity and specificity, as in comparison with gold customary, and its limitations. On this article, laboratory analysis of extreme acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is mentioned, with an emphasis on Ag-RDT and the advice to make use of it correctly in each day observe.

Fast Screening for Non-falciparum Malaria in Elimination Settings Utilizing Multiplex Antigen and Antibody Detection: Publish Hoc Identification of Plasmodium malariae in an Toddler in Haiti

Haiti is focusing on malaria elimination by 2025. The Grand’Anse division in southwestern Haiti experiences one-third to half of all nationally reported Plasmodium falciparum circumstances. Though there are historic experiences of Plasmodium vivax and Plasmodium malariae, right now, non-falciparum infections would stay undetected due to in depth use of falciparum-specific histidine-rich protein 2 (HRP2) fast diagnostic assessments (RDT) at well being amenities. A current case-control examine was performed in Grand’Anse to determine threat elements for P. falciparum an infection utilizing HRP2-based RDTs (n = 1,107).

Publish hoc multiplex Plasmodium antigenemia and antibody (IgG) detection by multiplex bead assay revealed one blood pattern optimistic for pan-Plasmodium aldolase, adverse for P. falciparum HRP2, and optimistic for IgG antibodies to P. malariae. Primarily based on this discovering, we chosen 52 samples with potential P. malariae an infection utilizing IgG and antigenemia knowledge and confirmed an infection standing by species-specific PCR. We confirmed one P. malariae an infection in a 6-month-old toddler with out journey historical past.

Congenital P. malariae couldn’t be excluded. Nevertheless, our finding-in mixture with historic experiences of P. malariae-warrants additional investigation into the presence and potential extent of non-falciparum malaria in Haiti. Moreover, we confirmed the usage of multiplex Plasmodium antigen and IgG detection in choosing samples of curiosity for subsequent PCR evaluation, thereby decreasing prices versus testing all out there samples by PCR. That is of particular use in low-transmission or eliminating settings the place infections are uncommon.

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